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Post-Operative Instructions: Biopsy


Pain Management

  • If possible, take ibuprofen (Advil®, Motrin®) and acetaminophen (Tylenol®) alternately. Begin with 600mg of ibuprofen, followed by 500mg of acetaminophen three hours later. Alternate between the two every three hours to maintain a six-hour schedule for each medication.
  • If a stronger pain medication is prescribed, follow the instructions provided, supplementing with acetaminophen and ibuprofen.
  • Keep a record of the medications taken, their dosages, and the time you take each one to monitor your intake.


  • Keep stitches around your lips moisturized with Vaseline® to reduce irritation.
  • Expect stitches to dissolve within a week; however, it is normal for them to fall out before or after this period and is no cause for concern.


  • Avoid acidic or spicy foods and drinks.
  • Be cautious with hot liquids due to possible numbness in the treated area following the procedure.


  • Anticipate increased swelling in the first 48 hours, peaking around day three, and decreasing after.

Oral Hygiene

  • Refrain from smoking.
  • Maintain oral hygiene through regular brushing and flossing.
  • Rinse your mouth gently with warm salt water 24 hours after the procedure for seven days.
  • If provided with medicated mouthwash, use it as directed, typically twice daily for a week starting 24 hours after the procedure.


  • Complete the course of any prescribed antibiotics as directed.


  • Rest and avoid strenuous activities immediately after the procedure.
  • Gradually increase activity levels as comfort improves.